Allison Janney
- Not Alone
2027 (voice)
- Miss You, Love You
2026 Diane Patterson
- Minions & Monsters
2026 Olivia (voice)
- The Dog Stars
2026 Darlene
- Everything's Going to Be Great
2025 Macy Smart
- Another Simple Favor
2025 Aunt Linda McLanden
- The Roses
2025 Eleanor
- The Creator
2023 Colonel Howell
- Minions & More Volume 2
2022 Madge Nelson (voice)
- Lou
2022 Executive Producer
- The People We Hate at the Wedding
2022 Donna
- To Leslie
2022 Nancy
- Breaking News in Yuba County
2021 Executive Producer
- Lazy Susan
2020 Velvet
- A West Wing Special to Benefit When We All Vote
2020 C.J. Cregg
- The Addams Family
2019 Margaux Needler (voice)
- Troop Zero
2019 Miss Massey
- Bad Education
2019 Pam Gluckin
- Bombshell
2019 Susan Estrich
- Ma
2019 Doctor Brooks
- Expedition Amelia
2019 Narrator (voice)
- The Night Is Young
2018 Wanda
- Sun Dogs
2017 Rose Chipley
- A Happening of Monumental Proportions
2017 Principal Nichols
- I, Tonya
2017 LaVona
- Miss Peregrine's Home for Peculiar Children
2016 Dr. Golan
- Tallulah
2016 Margo
- The Girl on the Train
2016 Detective Sgt. Riley
- Finding Dory
2016 Peach (voice)
- Spy
2015 Elaine Crocker
- The DUFF
2015 Dottie Piper
- Minions
2015 Madge Nelson (voice)
- Binky Nelson Unpacified
2015 Madge Nelson (voice)
- Mr. Peabody & Sherman
2014 Ms. Grunion (voice)
- Tammy
2014 Deb
- Days and Nights
2014 Elizabeth
- The Rewrite
2014 Professor Weldon
- Get On Up
2014 Kathy
- Struck by Lightning
2013 Sheryl Phillips
- Touchy Feely
2013 Bronwyn
- The Way Way Back
2013 Betty Thompson
- Trust Me
2013 Meg
- Bad Words
2013 Dr. Bernice Deagan
- Brightest Star
2013 The Astronomer
- A Thousand Words
2012 Samantha Davis
- Liberal Arts
2012 Professor Judith Fairfield
- Celia
2012 Celia
- Margaret
2011 Monica Patterson
- The Help
2011 Charlotte Phelan
- The Oranges
2011 Carol Ostroff
- Life During Wartime
2010 Trish Maplewood
- Love and Distrust
2010 Grechen (segment "Auto Motives")
- Away We Go
2009 Lily
- It's Still Me!
2009 Narrator (voice)
- 9 to 5: The Musical
2009 Violet Newstead
- Prop 8: The Musical
2008 Prop 8 Leader's #1 Wife
- Pretty Ugly People
2008 Suzanna
- Hairspray
2007 Prudy Pringleton
- Juno
2007 Bren MacGuff
- Over the Hedge
2006 Gladys (voice)
- Strangers with Candy
2006 Alice
- The Chumscrubber
2005 Allie Stiffle
- Our Very Own
2005 Joan Whitfield
- Winter Solstice
2004 Molly Ripkin
- Piccadilly Jim
2004 Eugenia Crocker
- Finding Nemo
2003 Peach (voice)
- How to Deal
2003 Lydia Martin
- Chicken Party
2003 Barbara Strasser
- The Hours
2002 Sally Lester
- Rooftop Kisses
2002 Melissa
- Nurse Betty
2000 Lyla
- Auto Motives
2000 Grechen
- American Beauty
1999 Barbara Fitts
- Drop Dead Gorgeous
1999 Loretta
- 10 Things I Hate About You
1999 Ms. Perky
- The Debtors
1999
- Six Days Seven Nights
1998 Marjorie
- Primary Colors
1998 Miss Walsh
- Celebrity
1998 Evelyn Isaacs
- The Object of My Affection
1998 Constance Miller
- The Impostors
1998 Maxine (Max)
- David and Lisa
1998 Alix
- ...First Do No Harm
1997 Dr. Melanie Abbasac
- Julian Po
1997 Lilah Leech
- Anita Liberty
1997 Gynecologist
- Private Parts
1997 Dee Dee
- The Ice Storm
1997 Dot Halford
- Path to Paradise: The Untold Story of the World Trade Center Bombing
1997 Assistant D.A.
- The Associate
1996 Sandy
- Walking and Talking
1996 Gum Puller
- Big Night
1996 Ann
- Faithful
1996 Saleslady
- Flux
1996 Heather
- Rescuing Desire
1996 Betsy
- Heading Home
1995 Mary Polanski
- Wolf
1994 Party Guest
- Dead Funny
1994 Jennifer
- The Cowboy Way
1994 NYPD Computer Operator
- Miracle on 34th Street
1994 Woman in Christmas Shop
- Blind Spot
1993 Doreen
- Who Shot Pat?
1989 Miss Penny
