Amy Madigan
- Gladys
2028 Gladys
- The Comebacker
2027
- Weapons
2025 Gladys
- Rebuilding
2025 Bess
- Off the Horse
2025 Bobbette
- Brooklyn, Minnesota
2024 Gail
- Bull Street
2024 Mary-Ann
- Go For Grandma
2023 Grandma
- Antlers
2021 Principal Booth
- The Hunt
2020 Ma
- The Last Full Measure
2020 Donna Burr
- Stuck
2019 Sue
- Gary's Walk
2019 Gloria
- A Crooked Somebody
2018 Joyce Vaughn
- American Woman
2018 Peggy
- Grey Lady
2017 Lola
- Rules Don't Apply
2016 Mrs. Bransford
- Buried Child
2016 Halie
- Sensitivity Training
2016 Nancy
- Shirin in Love
2014 Rachel
- Frontera
2014 Olivia
- The Lifeguard
2013 Justine
- Sweetwater
2013 Madame Bovary
- Future Weather
2012 Greta
- That's What I Am
2011 Principal Kelner
- Once Fallen
2010 Executive Producer
- Virginia
2010 Mrs. Tipton
- Doppelgänger
2009 Mom
- Living Proof
2008 Fran Visco
- Gone Baby Gone
2007 Bea McCready
- Winter Passing
2006 Lori Lansky
- Murder on Pleasant Drive
2006 Sherrie Davis
- Admissions
2004 Martha Brighton
- The Ranch
2004 Mary Larkin
- Unforgivable Blackness: The Rise and Fall of Jack Johnson
2004 Other Voices (voice)
- In the Land of Milk and Money
2004 Arlyne
- Horatio's Drive: America's First Road Trip
2003 Other Voices (voice)
- Is Your Mama a Llama?
2003 Narrator (voice)
- A Time for Dancing
2002 Jackie Russell
- Mark Twain
2002 (voice)
- Just a Dream
2002 Cindy Wilder
- The Laramie Project
2002 Reggie Fluty
- Shot in the Heart
2001 Bessie Gilmore
- The Sleepy Time Gal
2001 Maggie
- Pollock
2000 Peggy Guggenheim
- In the Name of the People
2000 Connie Murphy
- Having Our Say: The Delany Sisters' First 100 Years
1999 Amy Hill Hearth
- A Bright Shining Lie
1998 Mary Jane Vann
- With Friends Like These
1998 Hannah DiMartino
- Loved
1997 Brett Amerson
- Female Perversions
1996 Madelyn Stephens
- Riders of the Purple Sage
1996 Executive Producer
- And Then There Was One
1994 Roxy Ventola
- The Dark Half
1993 Liz Beaumont
- The Donner Party
1992 voice
- Lucky Day
1991 Kari
- Field of Dreams
1989 Annie Kinsella
- Uncle Buck
1989 Chanice Kobolowski
- Roe vs. Wade
1989 Sarah Weddington
- The Prince of Pennsylvania
1988 Carla Headlee
- The Revolt of Mother
1988 Sarah Penn
- Nowhere to Hide
1987 Barbara Cutter
- Fat Guy Goes Nutzoid
1986 Woman at funeral
- Twice in a Lifetime
1985 Sunny
- Alamo Bay
1985 Glory
- The Laundromat
1985 Deedee Johnson
- Streets of Fire
1984 McCoy
- Places in the Heart
1984 Viola Kelsey
- The Day After
1983 Alison Ransom
- Love Letters
1983 Wendy
- Travis McGee
1983 Billy Jean Bailey
- Love Child
1982 Terry Jean Moore
- The Ambush Murders
1982 Molly Slavin
- Victims
1982 Chloe Brill
- Crazy Times
1981 Marilyn
- The Ploughmen
Francie
- Ashley Wright
Donna Terry
