Anna Paquin
- True Spirit
2023 Julie Watson
- A Bit of Light
2022 Ella
- A Friend of the Family
2022 Mary Ann Broberg
- American Underdog
2021 Brenda Meoni/Brenda Warner
- Tell It to the Bees
2019 Jean Markham
- The Irishman
2019 Older Peggy Sheeran
- Modern Love
2019 Isabelle
- Flack
2019 Robyn
- Furlough
2018 Lily Benson
- The Parting Glass
2018 Producer
- Bellevue
2017 Annie Ryder
- Philip K. Dick's Electric Dreams
2017 Sarah
- Alias Grace
2017 Nancy Montgomery
- Broken
2016 Gemma
- Roots
2016 Nancy Holt
- The Good Dinosaur
2015 Ramsey (voice)
- X-Men: Days of Future Past
2014 Rogue
- The Affair
2014 Joanie Lockhart
- Straight A's
2013 Katherine
- Free Ride
2013 Producer
- Susanna
2013 Katie
- The Carrier
2012 Kim
- Scream 4
2011 Rachel
- Margaret
2011 Lisa Cohen
- The Romantics
2010 Lila Hayes
- Open House
2010 Jennie
- The Courageous Heart of Irena Sendler
2009 Irena Sendler
- True Blood
2008 Sookie Stackhouse
- Mosaic
2007 Maggie Nelson (voice)
- Trick 'r Treat
2007 Laurie
- Blue State
2007 Executive Producer
- Bury My Heart at Wounded Knee
2007 Elaine Goodale
- Phineas and Ferb
2007 Kristen (voice)
- X-Men: The Last Stand
2006 Marie / Rogue
- The Squid and the Whale
2005 Lili
- X2
2003 Rogue
- 25th Hour
2002 Mary D'Annuzio
- Darkness
2002 Regina
- Buffalo Soldiers
2002 Robyn Lee
- Finding Forrester
2000 Claire Spence
- Almost Famous
2000 Polexia Aphrodisia
- It's the Rage
2000 Annabel Lee
- X-Men
2000 Rogue
- She's All That
1999 Mackenzie Siler
- A Walk on the Moon
1999 Alison Kantrowitz
- Hurlyburly
1998 Donna
- Amistad
1997 Queen Isabella
- The Member of the Wedding
1997 Frankie Addams
- Fly Away Home
1996 Amy Alden
- Jane Eyre
1996 Young Jane Eyre
- The Piano
1993 Flora McGrath
