Anne Heche
- Wildfire: The Legend of the Cherokee Ghost Horse
2024 Diana Jones
- You're Killing Me
2023 Astrid
- Supercell
2023 Dr Quinn Brody
- Frankie Meets Jack
2023 In Memory Of
- Hardboiled
2022 Olive
- Girl in Room 13
2022 Janie
- What Remains
2022 Maureen
- 13 Minutes
2021 Tammy
- The Vanished
2020 Wendy
- The Best of Enemies
2019 Mary Ellis
- The Last Word
2017 Elizabeth
- Catfight
2017 Ashley
- My Friend Dahmer
2017 Joyce Dahmer
- Armed Response
2017 Riley
- Opening Night
2016 Brooke
- Looks Like Christmas
2016 Carol Montgomery
- Wild Card
2015 Roxy
- One Christmas Eve
2014 Nell Blakemore
- Nothing Left to Fear
2013 Wendy
- That's What She Said
2012 Dee Dee
- Arthur Newman
2012 Mina Crawley
- Final Cut: Ladies and Gentlemen
2012 (archive footage)
- Black November
2012 Barbara
- Blackout
2012 Dr. Debra Westen
- Cedar Rapids
2011 Joan Ostrowski-Fox
- Rampart
2011 Catherine
- Silent Witness
2011 Kate Robb
- Girl Fight
2011 Melissa
- The Other Guys
2010 Pamela Boardman (uncredited)
- Spread
2009 Samantha
- Toxic Skies
2008 Dr. Tess Martin
- Superman: Doomsday
2007 Lois Lane (voice)
- Suffering Man's Charity
2007 Helen Jacobsen
- What Love Is
2007 Laura
- Fatal Desire
2006 Tanya Sullivan
- Silver Bells
2005 Catherine O'Mara
- Sexual Life
2005 Gwen
- Bad Girls Behind Bars
2005 Jennifer (archive footage)
- Birth
2004 Clara
- The Dead Will Tell
2004 Producer
- Gracie's Choice
2004 Rowena Lawson
- Prozac Nation
2003 Dr. Sterling
- John Q
2002 Rebecca Payne
- On the Edge
2001 Director
- Auggie Rose
2000 Lucy Brown
- One Kill
2000 Capt. Mary Jane O'Malley
- If These Walls Could Talk 2
2000 Director
- The Third Miracle
1999 Roxanne
- Return to Paradise
1998 Beth Eastern
- Psycho
1998 Marion Crane
- Six Days Seven Nights
1998 Robin Monroe
- Wag the Dog
1997 Winifred Ames
- Volcano
1997 Dr. Amy Barnes
- I Know What You Did Last Summer
1997 Melissa Egan
- Donnie Brasco
1997 Maggie Pistone
- Subway Stories
1997 Pregnant Girl (segment "Manhattan Miracle")
- The Making of Volcano
1997 Herself/Host
- The Juror
1996 Juliet
- Wild Side
1996 Alex Lee / Johanna
- If These Walls Could Talk
1996 Christine Cullen
- Walking and Talking
1996 Laura
- Pie in the Sky
1996 Amy Morgan
- Kingfish: A Story of Huey P. Long
1995 Aileen Dumont
- Against the Wall
1994 Sharon Smith
- Milk Money
1994 Betty
- Girls in Prison
1994 Jennifer
- The Investigator
1994 Lucinda
- I'll Do Anything
1994 Claire
- A Simple Twist of Fate
1994 Tanny's Playmate (uncredited)
- The Adventures of Huck Finn
1993 Mary Jane Wilks
- An Ambush of Ghosts
1993 Denise
- O Pioneers!
1992 Marie
- Chasing Nightmares
Claire
