- Avatar 5
2031 Mo'at
- Avatar 4
2029 Mo'at
- The Naked Gun
2025 Chief Davis
- The Clock
2025 Elle Rivers
- Avatar: Fire and Ash
2025 Mo'at
- Rustin
2023 Dr. Anna Hedgeman
- Avatar: The Way of Water
2022 Mo'at
- Godzilla: King of the Monsters
2019 Senator Williams
- When I Was Young I Said I Would Be Happy
2016 Narrator (voice)
- Batman: Assault on Arkham
2014 Amanda Waller (voice)
- The Mortal Instruments: City of Bones
2013 Dorothea
- Home Again
2012 Dulsay Mooreland
- My Girlfriend's Back
2010 Constance
- Orphan
2009 Sister Abigail
- Superman/Batman: Public Enemies
2009 Amanda Waller (voice)
- Avatar
2009 Mo'at
- Rain
2008 Ms. Adams
- Breaking the Maya Code
2008 Narrator (voice)
- The Tower
2008 Evie
- Redemption: The Stan Tookie Williams Story
2004 Winnie Mandela
- Boycott
2001 Jo Ann Robinson
- Things Behind the Sun
2001 Judge
- Cora Unashamed
2000 Ma Jenkins
- Disappearing Acts
2000 Mrs. Swift
- End of Days
1999 Detective Margie Francis
- The Big Day
1999 Pearl
- NetForce
1999 Sandra Knight
- Funny Valentines
1999 Ethel B.
- A Touch of Hope
1999 Lily Keyes
- Batman Beyond: The Movie
1999 Virtual News Anchor #1 (voice)
- Race
1998 Lucinda Davis
- Little Girl Fly Away
1998 Dr. Geddes
- Final Justice
1998 Danielle Kline
- Things That Go Bump
1997 Harriet Napolean
- Face/Off
1997 Hollis Miller
- If These Walls Could Talk
1996 Jenny Ford
- All She Ever Wanted
1996 Marilyn
- Aladdin and the King of Thieves
1996 Oracle (voice)
- Tales from the Crypt: Demon Knight
1995 Irene
- White Dwarf
1995 Nurse Shabana
- Zooman
1995 Ash
- Jack Reed: One of Our Own
1995 Mrs. Harris
- Sliver
1993 Victoria Hendrix
- Benny & Joon
1993 Dr. Garvey
- RoboCop 3
1993 Bertha
- For Their Own Good
1993 Naomi Brinker
- Lifepod
1993 Mayvene
- The Ernest Green Story
1993 Daisy Bates
- The Disappearance of Christina
1993 Detective Davis
- The Importance of Being Earnest
1992 Miss Prism
- Psycho IV: The Beginning
1990 Fran Ambrose
- Murder in Mississippi
1990 Fannie Lee Chaney
- Common Ground
1990 Rachel Twymon
- Postcards from the Edge
1990 Julie Marsden
- Third Degree Burn
1989 Julie Cartwright (as C.C.H. Pounder)
- No Place Like Home
1989 Prue
- Run Till You Fall
1988 Janice
- Question of Faith
1988 Roberta
- Bagdad Cafe
1987 Brenda
- Resting Place
1986 Ada Johnson
- As Summers Die
1986 Priscilla
- Prizzi's Honor
1985 Peaches Altamont
- Go Tell It on the Mountain
1984 Deborah
- Booker
1984 Jane
- I'm Dancing as Fast as I Can
1982 Anne
- Union City
1980 Mother
- All That Jazz
1979 Nurse Blake
- Coriolanus
1979 Valeria
- Baby of the Family
Nurse Bloom
