Christine Lahti
- Bird in Hand
2026 Carlotta
- My Name Is Andrea
2022 Pariah
- Gloria: A Life
2020 Gloria Steinem
- A Beautiful Day in the Neighborhood
2019 Ellen
- Becks
2018 Ann
- Touched with Fire
2016 Sara
- Operator
2016 Beth Larsen
- The Steps
2016 Sherry
- Safelight
2015 Peg
- Hateship Loveship
2014 Eileen
- Petunia
2013 Felicia Petunia
- 8
2012 Kris Perry
- Touchback
2011 Thelma
- Flying Lessons
2010 Caroline Conway
- Obsessed
2009 Detective Monica Reese
- Operating Instructions
2009 Commander Helen Keller
- Yonkers Joe
2008 Janice
- Smart People
2008 Nancy
- Revenge of the Middle-Aged Woman
2004 Rose
- The Book of Ruth
2004 Maylene
- Out of the Ashes
2003 Gisella Perl
- Open House
2003 Samantha Morrow
- The Pilot's Wife
2002 Kathryn Lyons
- Women vs. Men
2002 Dana
- My First Mister
2001 Director
- An American Daughter
2000 Lyssa Dent Hughes
- Judgment Day: The Ellie Nesler Story
1999 Ellie Nesler
- Hope
1997 Emma Percy
- Subway Stories
1997 Red Shoe Woman (segment "The Red Shoes")
- A Weekend in the Country
1996 Ruth Oakley
- Pie in the Sky
1996 Ruby
- Hideaway
1995 Lindsey
- Lieberman in Love
1995 Director
- The Four Diamonds
1995 Dr. Burke / Sorceress Reptannehan
- Leaving Normal
1992 Darly
- The Fear Inside
1992 Meredith Cole
- The Good Fight
1992 Grace Cragin
- The Doctor
1991 Anne
- Crazy From the Heart
1991 Charlotte Bain
- Funny About Love
1990 Meg
- Gross Anatomy
1989 Dr. Rachel Woodruff
- No Place Like Home
1989 Zan Cooper
- Miss Firecracker
1989 Clara Archer
- Running on Empty
1988 Annie Pope
- Housekeeping
1987 Sylvie Fisher
- Stacking
1987 Kathleen Morgan
- Just Between Friends
1986 Sandy Dunlap
- Desert Bloom
1986 Voice of adult "Rose" (narrator)
- Love Lives On
1985 Marilyn
- Swing Shift
1984 Hazel Zanussi
- Single Bars, Single Women
1984 Elsie
- Ladies and Gentlemen, the Fabulous Stains
1982 Aunt Linda
- The Executioner's Song
1982 Brenda Nicol
- Whose Life Is It Anyway?
1981 Dr. Clare Scott
- The Henderson Monster
1980 Dr. Louise Casimir
- ...And Justice for All
1979 Gail Packer
- The Last Tenant
1978 Carol
- Dr. Scorpion
1978 Tania Reston
