- James the Second
2025 Milo
- Dom Irrera: Live from Las Vegas
2025 Writer
- Hey Arnold! The Jungle Movie
2018 Ernie (voice)
- I'm Dying Up Here
2017 Fitzy
- The Bronx Bull
2016 Joe E. Lewis
- Bob's Burgers
2011 The Nose (voice)
- Pound Puppies
2010 Princess (voice)
- Dom Irrera: Is This Thing On?
2009 Writer
- Back at the Barnyard - Cowman: The Uddered Avenger
2008 Duke (voice)
- Back at the Barnyard
2007 Duke
- The ½ Hour News Hour
2007 Lenny Varnadou - t-shirt salesman
- Barnyard
2006 Duke (voice)
- 'Til Death
2006 Doctor
- Ape
2003 Tony (Voice)
- Hey Arnold! The Movie
2002 Ernie Potts (voice)
- The 4th Tenor
2002 Petey (as Dominick Irrera)
- My Wife and Kids
2001
- The Big Lebowski
1998 Tony the Chauffeur
- The King of Queens
1998 Spero Demopolous
- Damon
1998 Carrol Fontain
- Hercules
1998 Achilles (voice)
- Hey Arnold! Arnold's Christmas
1996 Ernie Potts (voice)
- Everybody Loves Raymond
1996 Seth Stipe
- Captain Simian & the Space Monkeys
1996 Spydor (voice)
- Hey Arnold!
1996 Ernie Potts (voice)
- Full Frontal Comedy
1996 Host
- Dr. Katz, Professional Therapist
1995 Additional Writing
- Caroline in the City
1995 Cop
- The Drew Carey Show
1995 Stan
- The Silence of the Hams
1994 Gas Station Attendant
- Offsides
1994 Host
- Rocko's Modern Life
1993 Slippy (voice)
- Boy Meets World
1993 Bosco
- One-Night Stand: Dom Irrera: Command Performance
1992 Himself
- Public Enemy #2
1991 Detective #1
- Home Improvement
1991 Ed
- Parker Lewis Can't Lose
1990 Joey Pants
- Dream On
1990 Plumber
- That's Adequate
1989 Standup Comic
- Seinfeld
1989 Ronnie
- One Night Stand
1989
- Rodney Dangerfield: Nothin' Goes Right
1988 Writer
- Hollywood Shuffle
1987 Additional Writing
- She's the Sheriff
1987 Jim
- The Leftovers
1986 Mechanic
- It's Garry Shandling's Show
1986 Dominic Carbone
- The Golden Girls
1985 Waiter
- Splitz
1984 Vinnie Mamabasta
