- Animal Farm
2026 Frieda Pilkington (voice)
- The Hunger Games: Sunrise on the Reaping
2026 Drusilla Sickle
- La Bola Negra
2026 Isabelle Durand
- The Summer Book
2025 Producer
- Back in Action
2025 Ginny
- Wake Up Dead Man: A Knives Out Mystery
2025 Martha Delacroix
- The Deliverance
2024 Alberta Jackson
- Brothers
2024 Cath Munger
- Heart of Stone
2023 King of Diamonds
- Baba Yaga
2021 Chief (voice)
- Four Good Days
2021 Deb
- Swan Song
2021 Dr. Eve Scott
- Show of Titles
2021 "Dance a Little Closer" Performer
- Cruella
2021 Producer
- Hillbilly Elegy
2020 Mamaw
- In Search of the Sanderson Sisters: A Hocus Pocus Hulaween Takeover
2020 Cruella de Vil
- The Great Work Begins: Scenes from Angels in America
2020 Roy Cohn
- The Lavender Scare
2019 Narrator (voice)
- Let's Dance
2018 Segment: "Night Shift"
- The Green Fog
2018
- The Wife
2017 Joan Castleman
- Father Figures
2017 Helen Baxter
- Crooked House
2017 Lady Edith de Haviland
- What Happened to Monday
2017 Nicolette Cayman
- The Wilde Wedding
2017 Executive Producer
- Anesthesia
2016 Marcia Zarrow
- The Girl with All the Gifts
2016 Dr. Caroline Caldwell
- Warcraft
2016 Alodi (uncredited)
- The Great Gilly Hopkins
2015 Nonnie Hopkins
- Guardians of the Galaxy
2014 Nova Prime
- Low Down
2014 Gram
- 5 to 7
2014 Arlene Bloom
- Final Cut: Ladies and Gentlemen
2012 (archive footage)
- Albert Nobbs
2011 Screenplay
- Discovering Hamlet
2011 Gertrude (archive footage)
- Hoodwinked Too! Hood VS. Evil
2011 Granny (voice)
- Not My Life
2011 Narrator (voice)
- Gates of the Arctic
2008 Narrator (voice)
- Evening
2007 Mrs. Wittenborn
- Gabon The Last Eden
2007 Narrator
- Hoodwinked!
2005 Granny (voice)
- The Chumscrubber
2005 Carrie Johnson
- Heights
2005 Diana
- Nine Lives
2005 Maggie
- Tarzan II
2005 Kala (voice)
- The Stepford Wives
2004 Claire Wellington
- Strip Search
2004 Karen Moore
- Le Divorce
2003 Olivia Pace
- The Lion in Winter
2003 Eleanor of Aquitaine
- Brush with Fate
2003 Cornelia Engelbrecht
- In Search of the Jaguar
2003 Narrator
- The Safety of Objects
2002 Esther Gold
- South Pacific
2001 Executive Producer
- The Ballad of Lucy Whipple
2001 Executive Producer
- 102 Dalmatians
2000 Cruella de Vil
- Things You Can Tell Just by Looking at Her
2000 Dr. Elaine Keener (segments "This is Dr. Keener" and "Fantasies about Rebecca")
- Welcome to Hollywood
2000 Glenn Close
- Baby
2000 Executive Producer
- Cookie's Fortune
1999 Camille Dixon
- Tarzan
1999 Kala (voice)
- Sarah, Plain and Tall: Winter's End
1999 Sarah Witting
- SNL: The Best of Adam Sandler
1999 Gina (archive footage) (uncredited)
- Air Force One
1997 Kathryn Bennett
- In the Gloaming
1997 Janet
- Paradise Road
1997 Adrienne Pargiter
- In & Out
1997 Glenn Close (uncredited)
- Mars Attacks!
1996 Marsha Dale
- 101 Dalmatians
1996 Cruella de Vil
- Mary Reilly
1996 Mrs. Farraday
- Serving in Silence - The Margarethe Cammermeyer Story
1995 Executive Producer
- Anne Frank Remembered
1995 Diary Readings (voice)
- Journey
1995 Executive Producer
- The Paper
1994 Alicia Clark
- The House of the Spirits
1993 Ferula Trueba
- Skylark
1993 Executive Producer
- Lincoln
1992 Mary Todd Lincoln (voice)
- Hook
1991 Gutless
- Sarah, Plain and Tall
1991 Executive Producer
- Meeting Venus
1991 Karin Anderson
- Hamlet
1990 Gertrude
- Reversal of Fortune
1990 Sunny von Bülow / Narrator
- Immediate Family
1989 Linda Spector
- Dangerous Liaisons
1988 Marquise Isabelle de Merteuil
- The Legend of Sleepy Hollow
1988 Narrator (voice)
- Stones for Ibarra
1988 Sara Everton
- Electric Blue 29
1988 (archive footage)
- Fatal Attraction
1987 Alex Forrest
- Rabbit Ears - The Emperor and the Nightingale
1987 Narrator (voice)
- Jagged Edge
1985 Teddy Barnes
- Maxie
1985 Jan / Maxie
- The Natural
1984 Iris Gaines
- The Stone Boy
1984 Ruth Hillerman
- Something About Amelia
1984 Gail Bennett
- Greystoke: The Legend of Tarzan, Lord of the Apes
1984 Miss Jane Porter (voice) (uncredited)
- The Big Chill
1983 Sarah Cooper
- The World According to Garp
1982 Jenny Fields
- The Elephant Man
1982 Princess Alexandra
- Orphan Train
1979 Jessica
- Too Far to Go
1979 Rebecca Kuehn
- The Rules of the Game
1975 Neighbor
- Encore
Marie
- The Plague Monkeys
Narrator
- Sunset Boulevard
Producer
- The Midnight Library
Mrs.Elm
