Jennifer Tilly
- A Dog's Perfect Christmas
2026 Lucille
- The Adding Machine
2026 Mrs. Zero
- Sallywood
2024 Joann
- High Holiday
2021 Stephanie Corksey
- 7 Days to Vegas
2019 Jennifer
- Ray Meets Helen
2018 Ginger
- Cult of Chucky
2017 Tiffany
- A Cinderella Story: If the Shoe Fits
2016 Divine
- Unity
2015 Narrator (voice)
- The Secret Lives of Dorks
2013 Ms. Stewart
- Curse of Chucky
2013 Tiffany
- Return to Babylon
2013 Clara Bow
- Amelia's 25th
2013 Miss Celie
- 30 Beats
2012 Erika
- Made in Romania
2010 Jennifer Tilly
- The Making of Plus One
2010 Amber - the lead actress
- And Then There Were Fewer
2010 Bonnie Swanson (voice)
- Empire of Silver
2009 Mrs. Landdeck
- An American Girl: Chrissa Stands Strong
2009 Mrs. Rundell
- Bart Got a Room
2008 Melinda
- Deal
2008 Karen "Razor" Jones
- Inconceivable
2008 Salome 'Sally' Marsh
- The Caretaker
2008 Miss Perry
- The Pixar Story
2007 Celia Mae (voice) (archive footage)
- Intervention
2007 Jane
- The Initiation of Sarah
2006 Dr. Eugenia Hunter
- Tideland
2005 Queen Gunhilda
- Bailey's Billion$
2005 Dolores Pennington
- The Civilization of Maxwell Bright
2005 Dr. O'Shannon
- Chucky's Family Vacation
2005 Tiffany (Voice)
- Saint Ralph
2005 Nurse Alice
- Lil' Pimp
2005 Miss De La Croix (voice)
- Seed of Chucky
2004 Tiffany (voice) / Jennifer Tilly
- A Dairy Tale
2004 Grace (voice)
- Home on the Range
2004 Grace (voice)
- Perfect Opposites
2004 Elyse Steinberg
- Love on the Side
2004 Alma Kerns
- Second Best
2004 Carole
- Hollywood North
2004 Gillian Stevens
- El padrino: The Latin Godfather
2004 Sebeva
- The Haunted Mansion
2003 Madame Leota
- Happy End
2003 Edna
- Jericho Mansions
2003 Donna Cherry
- The Cat's Meow
2002 Louella Parsons
- The Women
2002 Crystal Allen
- The Magnificent Ambersons
2002 Fanny Minafer
- Strip Notes
2002
- Monsters, Inc.
2001 Celia (voice)
- Dancing at the Blue Iguana
2001 Jo
- Fast Sofa
2001 Ginger Quail
- Relative Evil
2001 Dot
- Sister Mary Explains It All
2001 Philomena Rostovich
- Dirt
2001 Hooker
- Gahan Wilson's The Kid
2001 The Waitress
- Hide and Seek
2000 Helen
- The Crew
2000 Ferris 'aka Maureen' Lowenstein
- Bruno
2000 Dolores
- Play It to the Bone
1999 Jennifer Tilly (Ringside Fan)
- The Muse
1999 Jennifer Tilly
- Do Not Disturb
1999 Cathryn Richmond
- Bartok the Magnificent
1999 Piloff (voice)
- Goosed
1999 Charlene
- Stuart Little
1999 Mrs. Stout (voice)
- Bride of Chucky
1998 Tiffany
- Music from Another Room
1998 Nina Swan
- Relax... It's Just Sex
1998 Tara
- Hoods
1998 Mary Crippa
- Liar Liar
1997 Samantha Cole
- The Wrong Guy
1997 Lynn Holden
- Bella Mafia
1997 Moyra Luciano
- Bound
1996 Violet
- Bird of Prey
1996 Kily Griffith
- American Strays
1996 Patty Mae
- Edie & Pen
1996 Edie
- The Pompatus of Love
1996 Tarzaan
- House Arrest
1996 Cindy Figler
- Embrace of the Vampire
1995 Marika
- Man with a Gun
1995 Rena Rushton / Kathy Payne
- The Getaway
1994 Fran Carvey
- Bullets Over Broadway
1994 Olive Neal
- Double Cross
1994 Melissa
- Heads
1994 Tina Abbot
- Made in America
1993 Stacy
- At Home with the Webbers
1993 Miranda Webber
- Shadow of the Wolf
1992 Igiyook
- Scorchers
1991 Talbot
- Bodyguard
1990 Melanie Whitaker
- Far from Home
1989 Amy
- Let It Ride
1989 Vicki
- The Fabulous Baker Boys
1989 Monica Moran
- High Spirits
1988 Miranda
- Remote Control
1988 Allegra
- Johnny Be Good
1988 Connie Hisler
- Rented Lips
1988 Mona Lisa
- Inside Out
1987 Amy
- He's My Girl
1987 Lisa
- Moving Violations
1985 Amy Hopkins
- No Small Affair
1984 Mona
- Imps*
1983 Joni
