- Tangled
2028 Mother Gothel
- Oswald
2027
- Madden
2026 Virginia Madden
- Life, Larry and the Pursuit of Unhappiness: An Almost History of America
2026 Mary Todd Lincoln
- Fixed
2025 Honey (voice)
- The Studio
2025 Maya Mason
- E. Jean Carroll v. Donald J. Trump
2024 E. Jean Carroll
- Agatha All Along
2024 Agnes O'Connor / Agatha Harkness
- Spider-Man: Across the Spider-Verse
2023 Doc Ock (voice)
- Tiny Beautiful Things
2023 Executive Producer
- Hotel Transylvania: Transformania
2022 Ericka (voice)
- Glass Onion: A Knives Out Mystery
2022 Claire Debella
- Marvel Studios' 2021 Disney+ Day Special
2021 Agnes / Agatha Harkness (archive footage)
- Marvel Studios Legends
2021 Agnes / Agatha Harkness (archive footage) (uncredited)
- WandaVision
2021 Agnes / Agatha Harkness
- The Shrink Next Door
2021 Phyllis Shapiro
- What If...?
2021 Agatha Harkness (voice)
- I Know This Much Is True
2020 Dessa Constantine
- Central Park
2020 Paige (voice)
- Die Hart
2020 Jillian Avery
- Transparent: Musicale Finale
2019 Raquel Fein
- Mrs. Fletcher
2019 Producer
- Private Life
2018 Rachel Biegler
- Hotel Transylvania 3: Summer Vacation
2018 Ericka (voice)
- Spider-Man: Into the Spider-Verse
2018 Doc Ock (voice)
- The Romanoffs
2018 Anka
- Flower
2017 Laurie
- A Bad Moms Christmas
2017 Carla
- Captain Fantastic
2016 Harper
- The Do-Over
2016 Becca
- Bad Moms
2016 Carla
- The Family Fang
2016 Young Camille
- Angie Tribeca
2016 Susan
- I Love Dick
2016 Co-Executive Producer
- She's Funny That Way
2015 Delta Simmons
- The Visit
2015 Mom
- The D Train
2015 Stacey Landsman
- Tomorrowland
2015 Ursula
- Len and Company
2015 Isabelle
- HAPPYish
2015 Lee Payne
- The Late Show with Stephen Colbert
2015 Evil Witch
- Bad Words
2014 Jenny Widgeon
- This Is Where I Leave You
2014 Annie Altman
- Transparent
2014 Raquel Fein
- Chozen
2014 Tracy
- Last Week Tonight with John Oliver
2014 Wife
- The Secret Life of Walter Mitty
2013 Odessa Mitty
- Afternoon Delight
2013 Rachel
- We're the Millers
2013 Edie Fitzgerald
- Timms Valley
2013 Daniel Myers
- Dark Around the Stars
2013 Judith
- Brooklyn Nine-Nine
2013 Eleanor
- Kroll Show
2013 Mikey's Mom
- Wanderlust
2012 Karen
- The Dictator
2012 Pregnant Woman
- The Greatest Event in Television History
2012 Sara Rush
- Girls
2012 Katherine Lavoyt
- The Newsroom
2012 Carrie
- Our Idiot Brother
2011 Janet
- Razzle Dazzle
2011 Writer
- Razzle Dazzle Part 2
2011 Writer
- Free Agents
2011 Helen Ryan
- Bob's Burgers
2011 Jessica (voice)
- Traffic Light
2011 Kate
- Mad Love
2011 Chef Linda Clay
- NTSF:SD:SUV::
2011 Marge
- How Do You Know
2010 Annie
- The Goods: Live Hard, Sell Hard
2009 Babs Merrick
- Parks and Recreation
2009 Jennifer Barkley
- Hung
2009 Claire
- Step Brothers
2008 Alice
- Revolutionary Road
2008 Milly Campbell
- Childrens Hospital
2008 Lamaze Teacher
- The Last Mimzy
2007 Naomi Schwartz
- The Holiday
2006 Bristol
- Four Kings
2006 Sharon
- A Lot Like Love
2005 Michelle
- Robot Chicken
2005 Mrs. Marquez / T-Shirt Girl #1 (voice)
- American Dad!
2005 Luli (voice)
- Anchorman: The Legend of Ron Burgundy
2004 Helen
- Wake Up, Ron Burgundy: The Lost Movie
2004 Helen
- Win a Date with Tad Hamilton!
2004 Angelica
- Around the Bend
2004 Sarah
- How to Lose a Guy in 10 Days
2003 Michelle Rubin
- Crossing Jordan
2001 Lily Lebowski
- Flushed
1999
- Hickory Hideout
1981 Jenny
- The Sisters Rosensweig
Gorgeous
- AbFab
Eddie
