Laura Linney
- Rode to Ruin
2027
- Onwards and Sideways
2026 Emma Dretzin
- American Classic
2026 Executive Producer
- Lanterns
2026 Lianna
- The American Revolution
2025 Sarah Logan Fisher / Sarah Morris Mifflin / Eliza Wilkinson / Eliza Lucas Pickney (voice)
- Black Rabbit
2025 Director
- Wildcat
2024 Regina O'Connor
- Suncoast
2024 Kristine
- The Miracle Club
2023 Chrissie Ahearn
- The Roads Not Taken
2020 Rita
- Falling
2020 Sarah (45 Yrs)
- The Great Work Begins: Scenes from Angels in America
2020 Hannah Pitt
- Determined to Persevere: The Valley Forge Encampment
2020 Narrator
- The Vote
2020
- Tales of the City
2019 Executive Producer
- Sink Sank Sunk
2018 Mitzi Mills
- The Dinner
2017 Claire Lohman
- Red Nose Day Actually
2017 Sarah (US version)
- Ozark
2017 Director
- Genius
2016 Louise Saunders
- Sully
2016 Lorrie Sullenberger
- Teenage Mutant Ninja Turtles: Out of the Shadows
2016 Chief Vincent
- Nocturnal Animals
2016 Anne Sutton
- Mr. Holmes
2015 Mrs. Munro
- BoJack Horseman
2014 Laura Linney (voice)
- The Fifth Estate
2013 Sarah Shaw
- Morning
2013 Doctor Goodman
- Hyde Park on Hudson
2012 Daisy
- The Details
2012 Lila
- Arthur Christmas
2011 North Pole Computer (voice)
- Sympathy for Delicious
2010 Nina Hogue
- The Big C
2010 Executive Producer
- The City of Your Final Destination
2009 Caroline Gund
- The Other Man
2008 Lisa
- John Adams
2008 Abigail Adams
- Breach
2007 Kate Burroughs
- The Savages
2007 Wendy Savage
- The Nanny Diaries
2007 Mrs. X
- The Hottest State
2007 Jesse
- Jindabyne
2006 Claire
- Driving Lessons
2006 Laura Marshall
- Man of the Year
2006 Eleanor Green
- Annie Oakley
2006 Narrator (voice)
- The Armenian Genocide
2006 Maria Jacobsen (voice)
- The Squid and the Whale
2005 Joan Berkman
- The Exorcism of Emily Rose
2005 Erin Bruner
- Mary Pickford
2005 Narrator
- American Dad!
2005 Doctor Gupta (voice)
- Kinsey
2004 Clara McMillen
- P.S.
2004 Louise Harrington
- Mystic River
2003 Annabeth Markum
- Love Actually
2003 Sarah
- The Life of David Gale
2003 Constance Hallaway
- The Mothman Prophecies
2002 Connie Mills
- The Laramie Project
2002 Sherry Johnson
- RI:SE
2002
- Wild Iris
2001 Iris Bravard
- Maze
2001 Callie
- F. Scott Fitzgerald: Winter Dreams
2001 Zelda Fitzgerald
- Further Tales of the City
2001 Mary Ann Singleton
- The House of Mirth
2000 Bertha Dorset
- You Can Count on Me
2000 Sammy
- Running Mates
2000 Lauren Hartman
- Lush
1999 Rachel Van Dyke
- Love Letters
1999 Melissa Gardner Cobb
- The Truman Show
1998 Meryl
- The Truman Show: Tru-Talk
1998 Hannah Gill
- More Tales of the City
1998 Mary Ann Singleton
- Absolute Power
1997 Kate Whitney
- King of the Hill
1997 Marlene (voice)
- Primal Fear
1996 Janet Venable
- Congo
1995 Dr. Karen Ross
- A Simple Twist of Fate
1994 Nancy Lambert Newland
- Dave
1993 Randi
- Searching for Bobby Fischer
1993 School Teacher
- Class of '61
1993 Lily Magraw
- Blind Spot
1993 Phoebe
- Frasier
1993 Charlotte Connor
- Tales of the City
1993 Mary Ann Singleton
- Lorenzo's Oil
1992 Young Teacher
- Law & Order
1990 Martha Bowen
- American Experience
1988 Narrator (voice)
- American Playhouse
1982 Mary Ann Singleton
- The Joy of Sex
Ruth Comfort
