- You're Dating a Narcissist!
2026 Judy
- F Valentine's Day
2026 Wendy
- The Mongoose
2026 Tara
- Spider-Man: Brand New Day
2026 May Parker
- High Tide
2024 Executive Producer
- Upgraded
2024 Claire
- Brothers
2024 Bethesda Waingro
- She Came to Me
2023 Katrina Trento
- A Better Half
2022 (voice)
- Delia's Gone
2022 Fran
- Spider-Man: No Way Home
2021 May Parker
- Human Capital
2020 Carrie Manning
- The King of Staten Island
2020 Margie Carlin
- Sarah Cooper: Everything's Fine
2020 Satan
- Beirut: An MCC Virtual TV Event
2020 Blue
- The Cold Open
2019
- Frankie
2019 Ilene
- Spider-Man: Far From Home
2019 May Parker
- I Hate Kids
2019 Christine Hurley
- Avengers: Endgame
2019 Aunt May
- After Everything
2018 Dr. Lisa Harden
- Dark Was the Night
2018 Margaret Lang
- Laboratory Conditions
2018 Emma Holloway
- The First Purge
2018 Dr. May Updale / Architect
- Spider-Man: Homecoming
2017 May Parker
- Citizen Jane: Battle for the City
2017 Jane Jacobs (voice)
- Captain America: Civil War
2016 May Parker
- Seed: The Untold Story
2016 Co-Producer
- Spare Parts
2015 Gwen Kolinsky
- Trainwreck
2015 The Dog Owner
- Love the Coopers
2015 Emma Newport
- The Big Short
2015 Cynthia Baum
- Love Is Strange
2014 Kate
- Loitering with Intent
2014 Producer
- The Rewrite
2014 Holly Carpenter
- She Said, She Said
2013 Marishka
- Parental Guidance
2012 Alice Simmons
- Inescapable
2012 Fatima
- The Ides of March
2011 Ida Horowicz
- Crazy, Stupid, Love.
2011 Kate
- The Lincoln Lawyer
2011 Maggie McPherson
- Salvation Boulevard
2011 Honey Foster
- Cyrus
2010 Molly Fawcett
- Amsterdam
2009 Donna
- The Wrestler
2008 Cassidy
- War, Inc.
2008 Natalie Hegalhuzen
- Wild Hogs
2007 Maggie
- Before the Devil Knows You're Dead
2007 Gina Hanson
- Grace Is Gone
2007 Woman at Pool
- Danika
2006 Danika Merrick
- Marilyn Hotchkiss' Ballroom Dancing & Charm School
2006 Meredith Morrison
- Factotum
2005 Laura
- Loverboy
2005 Sybil
- Alfie
2004 Julie
- Cabin Fever: Beneath the Skin
2004 Herself - Guest (uncredited)
- Anger Management
2003 Linda
- The Guru
2002 Lexi
- Just a Kiss
2002 Paula
- The Wild Thornberrys Movie
2002 Bree Blackburn (voice)
- In the Bedroom
2001 Natalie Strout
- Someone Like You...
2001 Liz
- Jenifer
2001 Nina Capelli
- The Watcher
2000 Dr. Polly Beilman
- What Women Want
2000 Lola
- Happy Accidents
2000 Ruby Weaver
- King of the Jungle
2000 Det. Costello
- Dirk and Betty
2000 Paris
- Slums of Beverly Hills
1998 Rita Abromowitz
- Only Love
1998 Evie
- My Own Country
1998 Mattie Vines
- Since You've Been Gone
1998 Tori (uncredited)
- Welcome to Sarajevo
1997 Nina
- A Brother's Kiss
1997 Missy
- Unhook the Stars
1996 Monica
- Four Rooms
1995 Margaret
- The Perez Family
1995 Dottie Perez
- Only You
1994 Faith Corvatch
- The Paper
1994 Martha Hackett
- Untamed Heart
1993 Caroline
- My Cousin Vinny
1992 Mona Lisa Vito
- Chaplin
1992 Mabel Normand
- Equinox
1992 Rosie Rivers
- Oscar
1991 Lisa Provolone
- Zandalee
1991 Remy
- Parker Kane
1990 April Haynes
- Supermom's Daughter
1987 Noelle Crandall
- Playing for Keeps
1986 Tracy
- The Flamingo Kid
1984 Mandy
- She Gets It from Me
Charlotte
