Mary McDonnell
- The Boroughs
2026 The Duchess
- VisionQuest
2026 Katerina Wells
- Broke
2025 Kathy Brandywine
- Twelve Dates 'Til Christmas
2025 Delilah
- The Fall of the House of Usher
2023 Madeline Usher
- The Witcher: Nightmare of the Wolf
2021 Lady Zerbst (voice)
- Rebel
2021 Helen Peterson
- Fargo
2014 Ruby Goldfarb
- Major Crimes
2012 Captain Sharon Raydor
- Scream 4
2011 Kate Roberts
- Margin Call
2011 Mary Rogers
- Hostile Makeover
2009 Rose Smithsonian
- Battlestar Galactica: Razor
2007 President Laura Roslin
- Mrs. Harris
2005 Vivian Schulte
- The Closer
2005 Captain Sharon Raydor
- Grey's Anatomy
2005 Virginia Dixon
- Crazy Like a Fox
2004 Amy Banks
- Battlestar Galactica
2004 Laura Roslin
- Veronica Mars
2004 Jane
- Nola
2003 Margaret Langworthy
- Battlestar Galactica
2003 President Laura Roslin
- The Locket
2002 Helen Staples
- Donnie Darko
2001 Rose Darko
- For All Time
2000 Laura Brown
- A Father's Choice
2000 Susan Shaw
- Mumford
1999 Althea Brockett
- Replacing Dad
1999 Linda Marsh
- Behind the Mask
1999 Mary Shushan
- Ryan Caulfield: Year One
1999 Rachel Caulfield
- Evidence of Blood
1998 Dora Overton
- You Can Thank Me Later
1998 Diane
- Two Voices
1997 Sybil Goldrich
- 12 Angry Men
1997 Judge
- Independence Day
1996 Marilyn Whitmore
- Woman Undone
1996 Teri Hansen
- Mariette in Ecstasy
1996 Prioress
- High Society
1995 Dott Emerson
- Blue Chips
1994 Jenny
- ER
1994 Eleanor Carter
- Touched by an Angel
1994 Sister Theodore Claire
- The American Clock
1993 Rose Baumler
- Sneakers
1992 Liz
- Passion Fish
1992 May-Alice Culhane
- Grand Canyon
1991 Claire
- Dances with Wolves
1990 Stands With A Fist
- The Making of 'Dances with Wolves'
1990 Herself
- Tiger Warsaw
1988 Paula Warsaw
- American Experience
1988 Narrator (voice)
- Matewan
1987 Elma Radnor
- Courage
1986 Gabriella Estrada
- Garbo Talks
1984 Lady Capulet
- E/R
1984 Eve Sheridan
- Money on the Side
1982 Terri
- Hallmark Hall of Fame
1951 Helen Staples
