- Last Train to Fortune
2026 Miss Maybelle
- Let's Have Kids!
2026 Sue
- The Dink
2026 Candace
- A Dog's Perfect Christmas
2026 Claire
- Easy's Waltz
2025
- BULLDOZER
2025 Kathy
- A Man on the Inside
2024 Mona Margadoff
- Book Club: The Next Chapter
2023 Carol
- Zoey's Extraordinary Christmas
2021 Maggie Clarke
- Nightmare Alley
2021 Mrs. Kimball
- Mr. Mayor
2021 Adriana
- Happiest Season
2020 Tipper
- 30 Rock: A One-Time Special
2020 Mary Steenburgen
- Zoey's Extraordinary Playlist
2020 Maggie Clarke
- Best Summer Ever
2020 Executive Producer
- Antiquities
2019 Dr. Margot
- Flannery
2019 Flannery O'Connor (voice)
- Bless the Harts
2019 Crystalynn (voice)
- On Becoming a God in Central Florida
2019 Ellen Joy Bonar
- Katie Says Goodbye
2018 Maybelle
- Book Club
2018 Carol
- The Conners
2018 Marcy Bellinger
- The Book of Love
2017 Julia Mureaux
- I Do... Until I Don't
2017 Cybil Burger
- The Discovery
2017 Interviewer
- Dean
2016 Carol
- The Good Place
2016 Teacher
- 7 Days in Hell
2015 Louisa Poole
- Jim Henson's Turkey Hollow
2015 Aunt Cly
- A Walk in the Woods
2015 Jeannie
- The Last Man on Earth
2015 Gail Klosterman
- Togetherness
2015 Linda
- Grace and Frankie
2015 Miriam
- Song One
2014 Karen Ellis
- The One I Love
2014 Thanks
- Brahmin Bulls
2013 Helen West
- Last Vegas
2013 Diana
- Orange Is the New Black
2013 Delia Powell
- Outlaw Country
2012 Anastasia Lee
- Fight for Your Right Revisited
2011 Café Patron
- The Help
2011 Elaine Stein
- Wilfred
2011 Catherine Newman
- Dirty Girl
2010 Peggy
- Weird: The Al Yankovic Story
2010 Mrs. Yankovic
- Justified
2010 Katherine Hale
- In the Electric Mist
2009 Bootsie Robicheaux
- The Proposal
2009 Grace Paxton
- Did You Hear About the Morgans?
2009 Emma Wheeler
- The Open Road
2009 Katherine
- Bored to Death
2009 Josephine
- Step Brothers
2008 Nancy Huff
- Four Christmases
2008 Marilyn
- The Brave One
2007 Carol
- Nobel Son
2007 Sarah Michaelson
- Numb
2007 Dr. Blaine
- Elvis & Anabelle
2007 Geneva Leigh
- Honeydripper
2007 Amanda Winship
- The Dead Girl
2006 Leah's Mother
- Marilyn Hotchkiss' Ballroom Dancing & Charm School
2006 Marienne Hotchkiss
- Inland Empire
2006 Visitor #2
- 30 Rock
2006 Diana Jessup
- Bye Bye Benjamin
2006 Executive Producer
- American Dad!
2005 (voice)
- Remembering Ragtime
2004 Mother (archive footage)
- It Must Be Love
2004 Clem Gazelle
- Elf
2003 Emily
- Hope Springs
2003 Joanie Fisher
- Casa de los Babys
2003 Gayle
- Mrs. Pilgrim Goes to Hollywood
2003 Mary
- Joan of Arcadia
2003 Helen Girardi
- Wish You Were Dead
2002 Sally Rider
- Living with the Dead
2002 Detective Karen Condrin
- Sunshine State
2002 Francine Pinkney
- Living with the Dead
2002 Detective Karen Condrin
- Nobody's Baby
2001 Estelle
- The Trumpet of the Swan
2001 Mother (voice)
- Life as a House
2001 Colleen Beck
- I Am Sam
2001 Dr. Blake
- Dinner for Five
2001
- Picnic
2000 Rosemary Sydney
- Curb Your Enthusiasm
2000 Mary Steenburgen
- Law & Order: Special Victims Unit
1999 Grace Rinato
- Noah's Ark
1999 Naamah
- About Sarah
1998 Sarah Elizabeth McCaffrey
- Becker
1998 Patient (uncredited)
- The Grass Harp
1996 Sister Ida
- Ink
1996 Producer
- Gulliver's Travels
1996 Mary Gulliver
- Nixon
1995 Hannah Nixon
- Powder
1995 Jessie Caldwell
- My Family
1995 Gloria
- Clifford
1994 Sarah Davis
- Pontiac Moon
1994 Katherine Bellamy
- It Runs in the Family
1994 Mrs. Parker (Mother)
- What's Eating Gilbert Grape
1993 Betty Carver
- Philadelphia
1993 Belinda Conine
- Frasier
1993 Marjorie (voice)
- Earth and the American Dream
1992 Reader (voice)
- Shelley Duvall's Bedtime Stories
1992 Narrator (voice)
- The Butcher's Wife
1991 Stella Keefover
- Back to the Future: Dickens of a Christmas
1991 Clara Clayton Brown (voice)
- Back to the Future
1991 Clara Clayton (voice)
- Back to the Future Part III
1990 Clara Clayton
- The Long Walk Home
1990 Narrator (voice)
- Parenthood
1989 Karen Buckman
- Miss Firecracker
1989 Elaine Rutledge
- The Attic: The Hiding of Anne Frank
1988 Miep Gies
- The Whales of August
1987 Young Sarah
- End of the Line
1987 Executive Producer
- Dead of Winter
1987 Julie Rose / Katie McGovern / Evelyn
- One Magic Christmas
1985 Ginny Grainger
- Tender Is the Night
1985 Nicole Diver (née Warren)
- Romantic Comedy
1983 Phoebe Craddock
- Cross Creek
1983 Marjorie Kinnan Rawlings
- Little Red Riding Hood
1983 Little Red Riding Hood a.k.a. Mary
- A Midsummer Night's Sex Comedy
1982 Adrian
- Faerie Tale Theatre
1982 Mary / Little Red Riding Hood
- Ragtime
1981 Mother
- Melvin and Howard
1980 Lynda Dummar
- Time After Time
1979 Amy Robbins
- Goin' South
1978 Julia Tate
- Happiness Isn't Everything
Audrey Veill
- Southern Discomfort
Mary Lou Dobson
