- The Muppet Show
2026 Maya Rudolph
- The Angry Birds Movie 3
2026 Matilda (voice)
- One Battle After Another
2025 Thanks
- IF
2024 Alligator (voice)
- The Second Best Hospital in the Galaxy
2024 Executive Producer
- Dream Productions
2024 Jean Dewberry (voice)
- His Three Daughters
2024 Executive Producer
- Teenage Mutant Ninja Turtles: Mutant Mayhem
2023 Cynthia Utrom (voice)
- Good Burger 2
2023 Maya Rudolph
- Digman!
2023 G.A.W.D. (voice)
- Poker Face
2023 Co-Executive Producer
- Who Killed Santa? A Murderville Murder Mystery
2022 Maya Rudolph
- Disenchanted
2022 Malvina Monroe
- Human Resources
2022 Bonnie LaCienega (voice)
- Loot
2022 Writer
- Baymax!
2022 Aunt Cass (voice)
- Crush
2022 Producer
- Sirens
2022 Executive Producer
- Licorice Pizza
2021 Gale
- A Clüsterfünke Christmas
2021 Shania Gary (Angel)
- The Mitchells vs. the Machines
2021 Linda (voice)
- Luca
2021 Daniela Paguro (voice)
- MacGruber
2021 Casey Janine Fitzpatrick
- The Willoughbys
2020 Nanny (voice)
- Hubie Halloween
2020 Mrs. Hennessey
- Sarah Cooper: Everything's Fine
2020 Writer
- Eater's Guide to the World
2020 Narrator (voice)
- Wine Country
2019 Naomi
- Booksmart
2019 Motivational Voice (voice)
- The Angry Birds Movie 2
2019 Matilda (voice)
- Thirsty
2019 The Mosquito
- Bless the Harts
2019 Betty Hart (voice)
- Life of the Party
2018 Christine Davenport
- The Happytime Murders
2018 Bubbles
- Forever
2018 Executive Producer
- We Don't Belong Here
2017 Joanne
- The Nut Job 2: Nutty by Nature
2017 Precious (voice)
- CHiPs
2017 Sgt. Hernandez
- Michael Bolton's Big, Sexy Valentine's Day Special
2017 Maya Rudolph
- The Emoji Movie
2017 Smiler (voice)
- Tour de Pharmacy
2017 Lucy Flerng
- A Christmas Story Live!
2017 Mother Parker
- Big Hero 6 The Series
2017 Aunt Cass (voice)
- Big Mouth
2017 Diane Birch / Connie the Hormone Monstress (voice)
- Nobodies
2017 Maya Rudolph
- The Angry Birds Movie
2016 Matilda (voice)
- Maggie's Plan
2016 Felicia
- Popstar: Never Stop Never Stopping
2016 Deborah
- Mr. Pig
2016 Eunice
- My Entire High School Sinking Into the Sea
2016 Verti (voice)
- Angie Tribeca
2016 Jackie Wilder
- The Good Place
2016 Judge Gen
- Sisters
2015 Brinda
- Strange Magic
2015 Griselda (voice)
- A Very Murray Christmas
2015 The Lounge Singer
- An SNL Valentine
2015 (archive footage)
- The Spoils Before Dying
2015 Fresno Foxglove
- Unbreakable Kimmy Schmidt
2015 Dionne Warwick
- Documentary Now!
2015 Anita
- The Grinder
2015 Jillian
- The Unbelievably Sweet Alpacas
2014 Giggles
- The Nut Job
2014 Precious (voice)
- Inherent Vice
2014 Petunia Leeway
- Big Hero 6
2014 Aunt Cass (voice)
- The Maya Rudolph Show
2014 Producer
- Turbo
2013 Burn (voice)
- Grown Ups 2
2013 Deanne McKenzie
- The Way Way Back
2013 Caitlyn
- Drunk History
2013 Griselda Blanco
- Brooklyn Nine-Nine
2013 U.S. Marshal Karen Haas
- Friends with Kids
2012 Leslie
- Fight for Your Right Revisited
2011 Girl in Limo 3
- Zookeeper
2011 Mollie the Giraffe (voice)
- Bridesmaids
2011 Lillian
- When Harry Met Sally 2 with Billy Crystal & Helen Mirren
2011 Maya Rudolph
- Up All Night
2011 Ava Alexander
- Portlandia
2011 Anita
- MacGruber
2010 Casey
- Grown Ups
2010 Deanne McKenzie
- The Women of SNL
2010 Various (archive footage)
- Presidential Reunion
2010 Michelle Obama
- Away We Go
2009 Verona De Tessant
- Saturday Night Live: The Best of Amy Poehler
2009 Various (archive footage)
- Cubed
2009 Maya Rudolph
- Possible Side Effects
2009 Alexandra
- Prop 8: The Musical
2008 California Gays and The People That Love Them
- Saturday Night Live Weekend Update Thursday
2008 Oprah Winfrey
- Kath & Kim
2008 Athena Scooberman
- Unsung
2008
- Shrek the Third
2007 Rapunzel (voice)
- Idiocracy
2006 Rita
- A Prairie Home Companion
2006 Molly
- Campus Ladies
2006
- 50 First Dates
2004 Stacy
- Wake Up, Ron Burgundy: The Lost Movie
2004 Kanshasha X
- Duplex
2003 Tara
- The Religetables
2002
- Chuck & Buck
2000 Jamila
- Duets
2000 Omaha Karaoke Hostess
- City of Angels
2000 Grace Patterson
- TV Funhouse
2000 Oprah Winfrey (voice)
- Family Guy
1999 Chloe (voice)
- Action
1999 Phina
- The Devil's Child
1997 Holly
- As Good as It Gets
1997 Policewoman
- Gattaca
1997 Delivery Nurse
- Chicago Hope
1994 Leah Martine
- The Simpsons
1989 Julia (voice)
- Saturday Night Live
1975 Annunale Announcer (voice) (uncredited)
- Grown Ups 3
Deanne McKenzie
