- What Happens Later
2023 Director
- Ithaca
2015 Director
- Fan Girl
2015 Mary Farrow
- Web Therapy
2011 Karen Sharpe
- Serious Moonlight
2009 Louise
- My Mom's New Boyfriend
2008 Marty Durand
- The Women
2008 Mary Haines
- The Deal
2008 Deidre Hearn
- Web Therapy
2008 Karen Sharpe
- My Best Friend's Girl
2008 Thanks
- In the Land of Women
2007 Sarah Hardwicke
- Against the Ropes
2004 Jackie Kallen
- In the Cut
2003 Frannie Avery
- Desert Saints
2002 Producer
- Kate & Leopold
2001 Kate McKay
- The Wedding Planner
2001 Executive Producer
- Hanging Up
2000 Eve Mozell Marks
- Proof of Life
2000 Alice Bowman
- Curb Your Enthusiasm
2000 Meg Ryan
- Lost Souls
2000 Producer
- City of Angels
1998 Maggie
- Hurlyburly
1998 Bonnie
- You've Got Mail
1998 Kathleen Kelly
- Northern Lights
1998 Executive Producer
- Addicted to Love
1997 Maggie
- Anastasia
1997 Anastasia (voice)
- Courage Under Fire
1996 Captain Karen Emma Walden
- French Kiss
1995 Producer
- Restoration
1995 Katharine
- When a Man Loves a Woman
1994 Alice Green
- I.Q.
1994 Catherine Boyd
- Sleepless in Seattle
1993 Annie Reed
- Flesh and Bone
1993 Kay Davies
- Prelude to a Kiss
1992 Rita Boyle
- The Doors
1991 Pamela Courson
- Joe Versus the Volcano
1990 DeDe / Angelica / Patricia Graynamore
- Captain Planet and the Planeteers
1990 Dr. Blight (voice)
- When Harry Met Sally...
1989 Sally Albright
- The Simpsons
1989 Dr. Swanson (voice)
- The Presidio
1988 Donna Caldwell
- D.O.A.
1988 Sydney Fuller
- Promised Land
1988 Bev Sykes
- Innerspace
1987 Lydia Maxwell
- Top Gun
1986 Carole
- Armed and Dangerous
1986 Maggie Cavanaugh
- Wildside
1985 Cally Oaks
- Charles in Charge
1984 Meagan Parker
- Amityville 3-D
1983 Lisa
- Amy and the Angel
1982 Denise
- Nature
1982 Host
- Rich and Famous
1981 Debby Blake, 18 Years
- Rabbit Ears: Goldilocks and the Three Bears
Narrator (voice)
- How I Met Your Dad
Future Sally Javits
