Melanie Griffith
- By Design
2026 Narrator (voice)
- The High Note
2020 Tess
- Howard
2018 Karen (archive footage)
- The Pirates of Somalia
2017 Maria Bahadur
- The Disaster Artist
2017 Jean Shelton
- J.L. Family Ranch
2016 Laura Lee
- Day Out of Days
2015 Kathy
- Nerd Herd
2015 Celeste
- Back to the Jurassic
2015 Tyra
- Yellow
2014 Patsy
- Automata
2014 Dr. Susan Dupré / Cleo (voice)
- Thirst
2014 Sue
- Call Me Crazy: A Five Film
2013 Kristin
- The Grief Tourist
2013 Betsy
- Dino Time
2012 Tyra (voice)
- A Turtle's Tale: Sammy's Adventures
2010 Snow (voice)
- Lethal Seduction
2005 Miranda Wells
- Shade
2003 Eve
- The Night We Called It a Day
2003 Barbara Marx
- Tempo
2003 Sarah
- Stuart Little 2
2002 Margalo (voice)
- Tart
2001 Diane Milford
- Cecil B. Demented
2000 Honey Whitlock
- Forever Lulu
2000 Lulu Mcafee
- The Book That Wrote Itself
2000 Melanie Griffith
- Crazy in Alabama
1999 Lucille Vinson
- RKO 281
1999 Marion Davies
- Celebrity
1998 Nicole Oliver
- Another Day in Paradise
1998 Sid
- Shadow of Doubt
1998 Kitt Devereux
- Lolita
1997 Charlotte Haze
- Mulholland Falls
1996 Katherine Hoover
- Now and Then
1995 Teeny
- Two Much
1995 Betty
- Buffalo Girls
1995 Dora DuFran
- Nobody's Fool
1994 Toby Roebuck
- Milk Money
1994 V
- Born Yesterday
1993 Billie Dawn
- Shining Through
1992 Linda Voss
- A Stranger Among Us
1992 Emily Eden
- Paradise
1991 Lily Reed
- Pacific Heights
1990 Patty Palmer
- The Bonfire of the Vanities
1990 Maria Ruskin
- In the Spirit
1990 Lureen
- Women and Men: Stories of Seduction
1990 Hadley (segment "Hills Like White Elephants")
- Working Girl
1988 Tess McGill
- Stormy Monday
1988 Kate
- The Milagro Beanfield War
1988 Flossie Devine
- Cherry 2000
1987 Edith 'E.' Johnson
- Something Wild
1986 Audrey Hankel
- Body Double
1984 Holly Body
- Fear City
1984 Loretta
- Roar
1981 Melanie
- Underground Aces
1981 Lucy
- She's in the Army Now
1981 Pvt. Sylvie Knoll
- The Star Maker
1981 Dawn Barnett Youngblood
- Golden Gate
1981 Karen
- The Cheryl Ladd Special
1979 Ellie - Waitress
- Daddy, I Don't Like It Like This
1978 Girl in Hotel Room
- Steel Cowboy
1978 Johnnie
- Joyride
1977 Susie
- The Garden
1977 Young Girl
- One on One
1977 The Hitchhiker
- Smile
1975 Karen
- Night Moves
1975 Delilah "Delly" Grastner
- The Drowning Pool
1975 Schuyler Devereaux
- The Harrad Experiment
1973 Student (uncredited)
- Smith!
1969 Extra (uncredited)
