Michelle Pfeiffer
- Oh. What. Fun.
2025 Claire
- Ant-Man and the Wasp: Quantumania
2023 Janet Van Dyne
- French Exit
2021 Frances Price
- Maleficent: Mistress of Evil
2019 Queen Ingrith
- Avengers: Endgame
2019 Janet Van Dyne
- Where Is Kyra?
2018 Kyra
- Ant-Man and the Wasp
2018 Janet Van Dyne / Wasp
- The Wizard of Lies
2017 Ruth Madoff
- mother!
2017 Woman
- Murder on the Orient Express
2017 Caroline Hubbard
- The Family
2013 Maggie Blake
- Dark Shadows
2012 Elizabeth Collins Stoddard
- Final Cut: Ladies and Gentlemen
2012 (archive footage)
- People Like Us
2012 Lillian Harper
- New Year's Eve
2011 Ingrid
- Chéri
2009 Lea
- Personal Effects
2009 Linda
- Stardust
2007 Lamia
- Hairspray
2007 Velma Von Tussle
- I Could Never Be Your Woman
2007 Rosie
- Sinbad: Legend of the Seven Seas
2003 Eris (voice)
- White Oleander
2002 Ingrid Magnussen
- I Am Sam
2001 Rita Harrison Williams
- Once Upon a Time: The Super Heroes
2001 Catwoman (archive footage)
- Original Sin
2001 Producer
- What Lies Beneath
2000 Claire Spencer
- A Midsummer Night's Dream
1999 Titania
- The Deep End of the Ocean
1999 Beth
- The Story of Us
1999 Katie Jordan
- The Prince of Egypt
1998 Tzipporah (voice)
- A Thousand Acres
1997 Producer
- To Gillian on Her 37th Birthday
1996 Gillian Lewis
- One Fine Day
1996 Executive Producer
- Up Close & Personal
1996 Tally Atwater
- Dangerous Minds
1995 Producer
- Wolf
1994 Laura Alden
- The Age of Innocence
1993 Ellen Olenska
- Batman Returns
1992 Catwoman / Selina
- Love Field
1992 Producer
- Frankie and Johnny
1991 Frankie
- The Russia House
1990 Katya Orlova
- The Fabulous Baker Boys
1989 Susie Diamond
- Dangerous Liaisons
1988 Madame Marie de Tourvel
- Married to the Mob
1988 Angela de Marco
- Tequila Sunrise
1988 Jo Ann Vallenari
- The Witches of Eastwick
1987 Sukie Ridgemont
- Tales from the Hollywood Hills: Natica Jackson
1987 Natica Jackson
- Amazon Women on the Moon
1987 Brenda (segment "Hospital")
- Sweet Liberty
1986 Faith Healy
- Ladyhawke
1985 Isabeau d'Anjou
- Into the Night
1985 Diana
- One Too Many
1985 Annie
- Scarface
1983 Elvira
- Grease 2
1982 Stephanie Zinone
- Callie & Son
1981 Sue Lynn Bordeaux
- Charlie Chan and the Curse of the Dragon Queen
1981 Cordelia Farenington III
- The Children Nobody Wanted
1981 Jennifer Williams
- Splendor in the Grass
1981 Ginny Stamper
- The Hollywood Knights
1980 Suzie Q
- Falling in Love Again
1980 Sue Wellington (1940's)
- The Solitary Man
1979 Tricia
- Turn of Mind
Amanda O'Toole
