Patrick Dempsey
- Memory of a Killer
2026 Angelo Doyle
- Threshold
2026 Executive Producer
- Dexter: Original Sin
2024 Aaron Spencer
- Thanksgiving
2023 Sheriff Eric Newlon
- Ferrari
2023 Piero Taruffi
- Disenchanted
2022 Robert Philip
- SurrealEstate
2021 Tom Quincy
- Devils
2020 Dominic Morgan
- Hurley
2019 Producer
- The Art of Racing in the Rain
2019 Producer
- The Truth About the Harry Quebert Affair
2018 Harry Quebert
- Red Nose Day Actually
2017 (US version)
- Bridget Jones's Baby
2016 Jack
- Flypaper
2011 Producer
- Transformers: Dark of the Moon
2011 Dylan
- Boys of Bonneville
2011 Narrator (voice)
- Valentine's Day
2010 Harrison Copeland
- Made of Honor
2008 Tom
- Freedom Writers
2007 Scott Casey
- Enchanted
2007 Robert Philip
- Private Practice
2007 Dr. Derek Shepherd
- Brother Bear 2
2006 Kenai (voice)
- Grey's Anatomy
2005 Derek Shepherd
- Iron Jawed Angels
2004 Ben Weissman
- Lucky 7
2003 Peter Connor
- Karen Sisco
2003
- Sweet Home Alabama
2002 Andrew Hennings
- The Emperor's Club
2002 Older Louis Masoudi
- Blonde
2001 Cass
- Scream 3
2000 Mark Kincaid
- Me and Will
1999 Fast Eddie
- Once and Again
1999
- Family Guy
1999 Patrick Dempsey (voice)
- Jeremiah
1998 Jeremiah
- Denial
1998 Sam
- Ava's Magical Adventure
1998 Director
- There's No Fish Food in Heaven
1998 The Stranger
- The Escape
1998 Clayton
- Crime and Punishment
1998 Rodya Raskolnikov
- The Treat
1998 Mike
- Will & Grace
1998 Matthew
- Hugo Pool
1997 Floyd Gaylen
- The Practice
1997 Paul Stewart
- 20,000 Leagues Under the Sea
1997 Pierre Arronax
- The Right to Remain Silent
1996 Tom Harris
- A Season in Purgatory
1996 Harrison Burns
- Outbreak
1995 Jimbo Scott
- Bloodknot
1995 Tom
- With Honors
1994 Everett Calloway
- Face the Music
1993 Charlie Hunter
- Bank Robber
1993 Billy
- For Better and for Worse
1993 Robert Faldo
- JFK: Reckless Youth
1993 John F. Kennedy
- Mobsters
1991 Meyer Lansky
- Run
1991 Charlie Farrow
- The General Motors Playwrights Theater
1991 James
- Coupe de Ville
1990 Robert 'Bobby' Libner
- The Word
1990
- Loverboy
1989 Randy Bodek
- Happy Together
1989 Chris Wooden
- The Super Mario Bros. Super Show!
1989 The Plant
- Some Girls
1988 Michael
- In a Shallow Grave
1988 Potter Daventry
- Can't Buy Me Love
1987 Ronald Miller
- In the Mood
1987 Ellsworth "Sonny" Wisecarver
- Out of This World
1987 Associate Producer
- Meatballs III: Summer Job
1986 Rudy
- A Fighting Choice
1986 Kellin Taylor
- Fast Times
1986 Mike Damone
- Heaven Help Us
1985 Corbet
- The Stuff
1985 Underground Stuff Buyer (uncredited)
- American Playhouse
1982 Potter Daventry
- Nightline
1980
