- Remarkably Bright Creatures
2026 Tova Sullivan
- 80 for Brady
2023 Betty
- Spoiler Alert
2022 Marilyn
- Love Letters
2020 Melissa Gardner
- National Theatre Live: All My Sons
2019 Kate Keller
- Little Evil
2017 Miss Shaylock
- Hello, My Name Is Doris
2015 Doris Miller
- The Amazing Spider-Man 2
2014 Aunt May
- Lincoln
2012 Mary Todd Lincoln
- The Amazing Spider-Man
2012 Aunt May
- The Desert of Forbidden Art
2011 Voice
- The Little Mermaid: Ariel's Beginning
2008 Marina Del Ray (voice)
- Two Weeks
2006 Anita Bergman
- Legally Blonde 2: Red, White & Blonde
2003 Victoria Rudd
- Say It Isn't So
2001 Valdine Wingfield
- David Copperfield
2001 Betsey Trotwood
- Where the Heart Is
2000 Mama Lil
- Beautiful
2000 Director
- A Cooler Climate
1999 Iris
- Saturday Night Live: Christmas
1999 Mom (archive footage)
- Merry Christmas, George Bailey
1997 Mrs. Bailey / Narrator
- Eye of God
1997 Thanks
- Homeward Bound II: Lost in San Francisco
1996 Sassy (voice)
- Eye for an Eye
1996 Karen McCann
- The Christmas Tree
1996 Director
- Forrest Gump
1994 Mrs. Gump
- Mrs. Doubtfire
1993 Miranda Hillard
- Homeward Bound: The Incredible Journey
1993 Sassy (voice)
- Soapdish
1991 Celeste Talbert
- Not Without My Daughter
1991 Betty Mahmoody
- Dying Young
1991 Producer
- Steel Magnolias
1989 M'Lynn Eatenton
- Punchline
1988 Lilah Krytsick
- Surrender
1987 Daisy Morgan
- Murphy's Romance
1985 Emma Moriarty
- Places in the Heart
1984 Edna Spalding
- Kiss Me Goodbye
1982 Kay
- Lily for President?
1982 Beth Barber
- Back Roads
1981 Amy Post
- Absence of Malice
1981 Megan Carter
- All the Way Home
1981 Mary Follet
- Smokey and the Bandit II
1980 Carrie
- Beyond the Poseidon Adventure
1979 Celeste Whitman
- Norma Rae
1979 Norma Rae
- The End
1978 Mary Ellen
- Hooper
1978 Gwen Doyle
- The Greatest Stuntman Alive
1978 Herself
- Smokey and the Bandit
1977 Carrie
- Heroes
1977 Carol Bell
- Stay Hungry
1976 Mary Tate Farnsworth
- Bridger
1976 Jennifer Melford
- Home for the Holidays
1974 Christine Morgan
- Hitched
1973 Roselle Bridgeman
- Mongo's Back in Town
1971 Vikki
- Maybe I'll Come Home in the Spring
1971 Denise "Dennie" Miller
- Marriage: Year One
1971 Jane Duden
- The Way West
1967 Mercy McBee
- Moon Pilot
1962 Beatnik Girl in Lineup (uncredited)
