Virginia Madsen
- Sheepdog
2026 Dr. Elecia Knox
- Street Smart
2026 Beth
- Lola
2024 Mona
- The Portrait
2023 Mags
- One Day as a Lion
2023 Valerie Brisky
- Give Me an A
2023 Coach Judy
- Prey for the Devil
2022 Dr. Peters
- Candyman
2021 Helen Lyle (voice)
- Operation Christmas Drop
2020 Congresswoman Angie Bradford
- Her Smell
2019 Ania Adamcyzk
- Spare Room
2018 Nat
- 1985
2018 Eileen
- It Was Always You, Helen
2018 Herself
- Better Watch Out
2017 Deandra Lerner
- A Change of Heart
2017 Deena
- Burn Your Maps
2016 Victoria
- Burning Bodhi
2016 Naomi
- Walter
2015 Karen
- Dead Rising: Watchtower
2015 Maggie
- Joy
2015 Terry
- An American Girl: Grace Stirs Up Success
2015 Mrs. Thomas
- Lost Boy
2015 Laura Harris
- Road to Capri
2015 Katherine
- All the Wilderness
2014 Abigail Charm
- Jake Squared
2014 Beth
- The Last Keepers
2013 Abigail Carver
- Crazy Kind of Love
2013 Augusta
- Anna Nicole
2013 Virgie Arthur
- The Hot Flashes
2013 Clementine Winks
- The Magic of Belle Isle
2012 Charlotte O'Neil
- Hornet's Nest
2012 Chief Judy Hammer
- Red Riding Hood
2011 Suzette
- Father of Invention
2010 Lorraine
- Wonder Woman
2009 Hippolyta (voice)
- The Haunting in Connecticut
2009 Sara Campbell
- I Know a Woman Like That
2009 Producer
- Amelia
2009 Dorothy Binney (uncredited)
- Diminished Capacity
2008 Charlotte
- The Number 23
2007 Agatha Sparrow / Fabrizia
- Cutlass
2007 Robin
- The Astronaut Farmer
2007 Mrs. Farmer
- Ripple Effect
2007 Executive Producer
- A Prairie Home Companion
2006 Dangerous Woman
- Firewall
2006 Beth Stanfield
- Stuart Little 3: Call of the Wild
2005 The Beast (voice)
- Scooby-Doo! in Where's My Mummy?
2005 Cleopatra (voice)
- Brave New Girl
2004 Wanda Lovell
- Sideways
2004 Maya
- Nobody Knows Anything!
2004 Prison Lawyer
- Artworks
2003 Emma Becker
- Tempted
2003 Emma Burke
- American Gun
2002 Penny Tillman
- Crossfire Trail
2001 Anne Rodney
- Lying in Wait
2001 Vera Miller
- Just Ask My Children
2001 Brenda Kniffen
- Almost Salinas
2001 Clare
- Full Disclosure
2001 Brenda Hopkins
- After Sex
2000 Traci
- Children of Fortune
2000 Ingrid Bast
- The Haunting
1999 Jane
- The Florentine
1999 Molly
- Ballad of the Nightingale
1999 Mo Lewis
- Ambushed
1998 Lucy Monroe
- The Apocalypse Watch
1997 Karin De Vries
- The Rainmaker
1997 Jackie Lemancyzk
- Ghosts of Mississippi
1996 Dixie DeLaughter
- Just Your Luck
1996 Kim
- The Prophecy
1995 Katherine Henley
- Blue Tiger
1994 Gina Hayes
- Caroline at Midnight
1994 Susan Prince
- Bitter Vengeance
1994 Annie Westford
- Linda
1993 Linda Cowley
- Candyman
1992 Helen Lyle
- A Murderous Affair: The Carolyn Warmus Story
1992 Carolyn Warmus
- Highlander II: The Quickening
1991 Louise Marcus
- Ironclads
1991 Betty Stuart
- Becoming Colette
1991 Polaire
- Love Kills
1991 Rebecca Bishop
- Victim of Love
1991 Carla Simmons
- The Hot Spot
1990 Dolly Harshaw
- Heart of Dixie
1989 Delia June Curry
- Third Degree Burn
1989 Anne Scholes
- Hot to Trot
1988 Allison Rowe
- Gotham
1988 Rachel Carlyle
- Mr. North
1988 Sally Boffin
- Zombie High
1987 Andrea
- Slam Dance
1987 Yolanda Caldwell
- Long Gone
1987 Dixie Lee Boxx
- Modern Girls
1986 Kelly
- Fire with Fire
1986 Lisa Taylor
- Creator
1985 Barbara Spencer
- The Hearst and Davies Affair
1985 Marion Davies
- Dune
1984 Princess Irulan
- Electric Dreams
1984 Madeline Robistat
- A Matter of Principle
1984 Lou Ellen Purdy
- Class
1983 Lisa
