Winona Ryder
- Stranger Things: Tales from '85
2026 Thanks
- Beetlejuice Beetlejuice
2024 Lydia
- Haunted Mansion
2023 Pat (uncredited)
- Gone in the Night
2022 Kath
- Sarah Cooper: Everything's Fine
2020 Lacey Groin
- The Plot Against America
2020 Evelyn Finkel
- Destination Wedding
2018 Lindsay
- The Pacer
2017
- Author: The JT LeRoy Story
2016 Herself
- Stranger Things
2016 Joyce Byers
- Experimenter
2015 Alexandra "Sasha" Milgram
- Show Me a Hero
2015 Vinni Restiano
- Turks & Caicos
2014 Melanie Fall
- Homefront
2013 Sheryl Marie Mott
- Drunk History
2013 Mary Dyer
- Frankenweenie
2012 Elsa Van Helsing (voice)
- The Iceman
2012 Deborah Kuklinski
- The Letter
2012 Martine Jamison
- Stay Cool
2011 Scarlet Smith
- The Dilemma
2011 Geneva Brannen
- Black Swan: Metamorphosis
2011 Thanks
- Black Swan
2010 Beth Macintyre / The Dying Swan
- When Love Is Not Enough: The Lois Wilson Story
2010 Lois Wilson
- The Private Lives of Pippa Lee
2009 Sandra Dulles
- Star Trek
2009 Amanda Grayson
- Water Pills
2009 Carrie
- The Informers
2008 Cheryl Moore
- The Last Word
2008 Charlotte Morris
- The Ten
2007 Kelly La Fonda
- Sex and Death 101
2007 Death Nell / Gillian De Raisx (#101)
- The Darwin Awards
2007 Siri Taylor
- Welcome
2007 Cynthia
- A Scanner Darkly
2006 Donna Hawthorne
- The Heart Is Deceitful Above All Things
2004 Psychologist
- Cabin Fever: Beneath the Skin
2004 (archive footage) (uncredited)
- The Day My God Died
2003 Producer
- Mr. Deeds
2002 Babe Bennett
- S1m0ne
2002 Nicola Anders
- Zoolander
2001 Winona Ryder (uncredited)
- Autumn in New York
2000 Charlotte Fielding
- Lost Souls
2000 Maya Larkin
- Girl, Interrupted
1999 Executive Producer
- Strangers with Candy
1999 Fran
- Celebrity
1998 Nola
- Alien Resurrection
1997 Call
- The Crucible
1996 Abigail Williams
- Boys
1996 Patty Vare
- How to Make an American Quilt
1995 Finn Dodd
- Dr. Katz, Professional Therapist
1995 Additional Writing
- Reality Bites
1994 Lelaina Pierce
- Little Women
1994 Jo March
- Friends
1994 Melissa Warburton
- The House of the Spirits
1993 Blanca Trueba
- The Age of Innocence
1993 May Welland
- Bram Stoker's Dracula
1992 Mina Murray / Elisabeta
- The Larry Sanders Show
1992 Winona Ryder
- Night on Earth
1991 Corky
- Edward Scissorhands
1990 Kim
- Mermaids
1990 Charlotte Flax
- Welcome Home, Roxy Carmichael
1990 Dinky Bossetti
- Heathers
1989 Veronica
- Great Balls of Fire!
1989 Myra Gale Brown
- The Simpsons
1989 Allison Taylor (voice)
- Beetlejuice
1988 Lydia
- 1969
1988 Beth Carr
- Square Dance
1987 Gemma
- Lucas
1986 Rina
