John Lithgow
- Jimpa
2026 Jimpa
- Giant
2026 Roald Dahl
- The Rule of Jenny Pen
2025 Executive Producer
- Cabrini
2024 Mayor Gould
- Spellbound
2024 Bolinar (voice)
- Art Happens Here with John Lithgow
2024 Executive Producer
- Conclave
2024 Tremblay
- Sharper
2023 Richard Hobbes
- Killers of the Flower Moon
2023 Prosecutor Peter Leaward
- Chez Bob
2022
- The Bubble
2022 Tom the Studio Chairman
- Live in Front of a Studio Audience: The Facts of Life and Diff'rent Strokes
2021 Philip Drummond
- Myths and Hymns
2021
- Emily @ the Edge of Chaos
2021 Sir Isaac Newton (voice)
- Show of Titles
2021 "There's No Business Like Show Business" Performer
- Late Night
2019 Walter Lovell
- Pet Sematary
2019 Jud Crandall
- Bombshell
2019 Roger Ailes
- The Tomorrow Man
2019 Ed Hemsler
- The Investigation: A Search for the Truth in Ten Acts
2019 President Donald J. Trump
- Pet Sematary: The Tale of Timmy Baterman
2018 Jud Crandall
- Beatriz at Dinner
2017 Doug Strutt
- Daddy's Home 2
2017 Don
- Pitch Perfect 3
2017 Fergus
- Hickory Dickory Doc
2017 Himself
- The Accountant
2016 Lamar Blackburn
- Ode to Joy: Beethoven's Symphony No. 9
2016 Narrator
- Miss Sloane
2016 Senator Ronald Sperling
- Lord John
2015
- Best of Enemies
2015 Voice of Gore Vidal
- Interstellar
2014 Donald
- Love Is Strange
2014 Ben
- The Homesman
2014 Reverend Alfred Dowd
- The Jungle Bunch 2: The Great Treasure Quest
2014 Maurice (voice)
- 9 Kisses
2014 Man in Club
- National Theatre Live: The Magistrate
2013 Posket
- Shrek Stories
2013 Lord Farquaad (voice)
- Timms Valley
2013 Ol' Gregory Timms
- The Campaign
2012 Glen Motch
- This Is 40
2012 Oliver
- Rise of the Planet of the Apes
2011 Charles Rodman
- New Year's Eve
2011 Jonathan Cox (uncredited)
- Leap Year
2010 Jack Brady
- Confessions of a Shopaholic
2009 Edgar West
- Miracle in a Box: A Piano Reborn
2009 Narrator
- Car of the Future
2008 Narrator
- Sangre
2006 Cafe chef and owner
- Dreamgirls
2006 Jerry Harris
- The Great Robot Race: The DARPA Grand Challenge
2006 Narrator
- The Best of The Tony Awards: The Plays
2006 René Gallimard (segment "M. Butterfly")
- Einstein's Big Idea
2005 Narrator (voice) U.S. edition
- The Life and Death of Peter Sellers
2004 Blake Edwards
- Kinsey
2004 Alfred Seguine Kinsey
- Shrek 3-D
2004 Ghost of Farquaad (voice)
- Dogs and More Dogs
2004 Narrator
- Footloose: A Modern Musical
2004 Thanks
- Bark, George
2003
- Orange County
2002 Bud Brumder
- Shrek
2001 Lord Farquaad (voice)
- Shrek in the Swamp Karaoke Dance Party
2001 Lord Farquaad (singing voice)
- Rugrats in Paris: The Movie
2000 Jean-Claude (voice)
- 95 Worlds and Counting
2000 Narrator
- Don Quixote
2000 Executive Producer
- Tales from the Crypt: The Robert Zemeckis Collection
1999 Dr. Oscar Charles
- Saturday Night Live: 25th Anniversary Special
1999 (archive footage)
- A Civil Action
1998 Judge Walter J. Skinner
- Homegrown
1998 Malcolm / Robert Stockman
- Johnny Skidmarks
1998 Sergeant Larry Skovik
- Officer Buckle and Gloria
1997 Narrator (voice)
- Hollow Point
1996 Thomas Livingston
- Special Effects: Anything Can Happen
1996 Narrator
- The Tuskegee Airmen
1995 Senator Conyers
- Redwood Curtain
1995 Laird Riordan
- My Brother's Keeper
1995 Tom Bradley / Bob Bradley
- A Good Man in Africa
1994 Arthur Fanshawe, British High Commissioner
- Princess Caraboo
1994 Professor Wilkinson
- Silent Fall
1994 Dr. Rene Harlinger
- The Pelican Brief
1993 Smith Keen
- Cliffhanger
1993 Qualen
- The Wrong Man
1993 Phillip Mills
- Love, Cheat & Steal
1993 Paul Harrington
- Sylvester and the Magic Pebble
1993 Narrator
- The Country Mouse & the City Mouse: A Christmas Tale
1993 Alexander (voice)
- Raising Cain
1992 Carter Nix / Cain / Dr. Nix / Josh / Margo
- Ricochet
1991 Earl Talbott Blake
- At Play in the Fields of the Lord
1991 Leslie Huben
- The Boys
1991 Artie Margulies
- Memphis Belle
1990 Bruce Derringer
- Ivory Hunters
1990 Robert Carter
- Amazing Stories: The Movie II
1990 John Walters
- Out Cold
1989 Dave
- Traveling Man
1989 Ben Cluett
- Distant Thunder
1988 Mark Lambert
- Harry and the Hendersons
1987 George Henderson
- Baby Girl Scott
1987 Neil Scott
- The Amazing Bone
1987 Narrator
- The Manhattan Project
1986 John Mathewson
- Resting Place
1986 Maj. Kendall Laird
- Santa Claus: The Movie
1985 B.Z.
- Mesmerized
1985 Oliver Thompson
- Footloose
1984 Rev. Shaw Moore
- 2010
1984 Dr. Walter Curnow
- The Adventures of Buckaroo Banzai Across the 8th Dimension
1984 Lord John Whorfin
- The Glitter Dome
1984 Sgt. Marty Wellborn
- Goldilocks and the Three Bears
1984 Goldilocks' Father
- 2010 : The Odyssey Continues
1984 Himself
- Terms of Endearment
1983 Sam Burns
- The Day After
1983 Joe Huxley
- Twilight Zone: The Movie
1983 Valentine
- The World According to Garp
1982 Roberta Muldoon
- I'm Dancing as Fast as I Can
1982 Mr. Brunner
- Not in Front of the Children
1982 Richard Carruthers
- Blow Out
1981 Burke
- The Oldest Living Graduate
1980 Clarence
- Big Blonde
1980 Herbie Morse
- Mom, the Wolfman and Me
1980 Wally
- All That Jazz
1979 Lucas Sergeant
- Rich Kids
1979 Paul Philips
- The Big Fix
1978 Sam Sebastian
- Secret Service
1977 Capt. Thorne
- Obsession
1976 Robert Lasalle
- The Country Girl
1974 Paul Unger
